Polynucleotide · MFDS Class IV
LizneLyzene PN
MIMISOME Clinic Busan Deokcheon · 33 Mandeok-daero, Buk-gu, Busan (2–3F) · 3 min from Deokcheon Station Exit 12
A Korean-made PN skin booster whose main ingredient is polynucleotide (PN) derived from salmon. Approved by the Korean MFDS as a Class IV medical device (tissue-repair biomaterial) after a clinical study in about 250 Korean patients, it is used to care for larger areas with little burden. It is done with numbing cream.
From ₩150,0001ccVAT excl.
- Duration
- 30 min
- Anesthesia
- Numbing cream
- Pain
- ●●○○○
- Downtime
- 1–2 days
- Results
- From 2–4 weeks
- Recommended course
- 3 sessions, 2–4 weeks apart
How it works
In the skin, PN supplies the material and signals cells need to repair damage and build collagen and elastic fibres, and it holds water to stabilise the environment within the skin. It belongs to the same family as Rejuran and is placed at regular intervals in the upper dermis to act evenly across the whole face. A programme is usually 3 sessions at 2–4 week intervals.
Ideal for
- Fine lines and roughened texture
- Dry, lacklustre skin
- Caring for a large area such as the whole face with little burden
- Continuing PN skin boosters on a regular basis
FAQ
What is Lizne?
A Korean-made PN skin booster whose main ingredient is polynucleotide (PN) derived from salmon. Approved by the Korean MFDS as a Class IV medical device (tissue-repair biomaterial) after a clinical study in about 250 Korean patients, it is used to care for larger areas with little burden. It is done with numbing cream.
When do results from Lizne start to show?
Regeneration builds gradually; our in-clinic guide is that changes in texture and glow begin to show around 2–4 weeks and are most visible towards the end of the programme.
How long do Lizne results last?
How long results last varies widely with skin condition and lifestyle. Our in-clinic guide is usually 3 sessions at 2–4 week intervals followed by a top-up every 3–6 months, with the timing decided in consultation based on your progress.
Does Lizne hurt? Is anesthesia used?
Anesthesia: Numbing cream. Discomfort is about 2 on a 5-point scale.
What is the downtime after Lizne — swelling and bruising?
Needle marks and swelling are common and usually settle within 1–2 days; bruises fade within 1–2 weeks. Avoid alcohol, saunas and strenuous exercise on the day of treatment. If anything feels different from what you were told, let us know in chat.
How many Lizne sessions are needed, and how far apart?
Our in-clinic guide is usually 3 sessions, 2–4 weeks apart; the number and spacing of sessions are decided in consultation.
How much does Lizne cost?
From ₩150,000 (1cc) · VAT excl. It varies by area and amount and is confirmed after consultation.
How long does a session of Lizne take?
A session takes about 30 min (numbing and preparation time not included).
Pairs well with
- Lifting devices — Regenerate after tightening
Aftercare & notes
- Needle marks・swelling a few days
- Swelling, bruising, lumps or rarely infection may occur; rare reactions and their care are explained at consultation